The Retina Division of The Wilmer Eye Institute at The Johns Hopkins University School of Medicine Presents MACULA 2010 Saturday, January 23, 2010 The Johns Hopkins University School of Medicine Thomas B. Turner Building Baltimore, Maryland Activity Directors: Neil Bressler, MD Diana Do, MD Quan Dong Nguyen, MD, MSc DESCRIPTION Over the past several years, there is a growing body of medical evidence that demonstrates a clear biologic rationale for targeting vascular endothelial growth factors (VEGFs) in the treatment of neovascular AMD, diabetic retinopathy, and venous occlusive disease. This area of investigation is relatively new, and most ophthalmologists are not aware of the myriad growth factors and their potential role in AMD, diabetic retinopathy, and venous occlusive disease. There is a need to understand these new tools for assessing outcomes and also to understand data based on visual acuity loss measurements from clinical trials of these new agents. Furthermore, it is important to review the role of imaging studies, especially optical coherence tomography, in the management of these ocular conditions. Thus, this new therapeutic approach for neovascular AMD, diabetic retinopathy, and venous occlusive disease has been evolving over the past three years and is an area of great interest both to ophthalmologists who treat these diseases and to those who refer these cases for further management. Presentations will be chosen to emphasize new information on the use of VEGF inhibitors and pharmacologic agents in the management of these diseases. In addition, cases will be chosen which highlight new information being reported by the Diabetic Retinopathy Clinical Research Network and other randomized clinical trials. WHO SHOULD ATTEND This activity is intended for Ophthalmologists, Retina Specialists, Residents, Fellows, and Eye care professionals. OBJECTIVES After attending this activity, the participant will demonstrate the ability to: - Recognize the role of angiogenesis in AMD and evaluate various treatment intervals for eyes undergoing therapy with VEGF inhibitors. - Evaluate recent clinical studies evaluating treatments for macular edema due to retinal vein occlusion. - Recognize the role of spectral domain OCT in the management of eyes with neovascular AMD. - Review the current and emerging therapies for treating non-neovascular AMD. - Summarize evidence of the role of ranibizumab for diabetic macular edema. - Determine which patients are appropriate for laser treatment in eyes with diabetic macular edema. - Diagnose choroidal melanoma and review treatment options. - Be familiar with the management of diabetic retinopathy and the new results from the clinical trials conducted by the Diabetic Retinopathy Clinical Research Network. Accreditation Statement The Johns Hopkins University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Credit Designation Statement The Johns Hopkins University School of Medicine designates this educational activity for a maximum of 8.0 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity. Policy on Speaker and Provider Disclosure It is the policy of The Johns Hopkins University School of Medicine that the speaker and provider disclose real or apparent conflicts of interest relating to the topics of this educational activity, and also disclose discussions of unlabeled/unapproved uses of drugs or devices during their presentation(s). The Johns Hopkins University School of Medicine OCME has established policies in place that will identify and resolve all conflicts of interest prior to this educational activity. Detailed disclosure will be made in the activity handout materials. GENERAL INFORMATION Registration January 23, 2010 ? 7:00 am - 7:30 am Location Thomas B. Turner Building The Johns Hopkins University School of Medicine 720 Rutland Avenue Baltimore, Maryland 21205 The Turner Building is located on Rutland Avenue at Monument Street. Directions and campus parking information are available on our website under the contact and travel section at www.HopkinsCME.edu. Handicapped parking is available in the nearby Rutland Garage. Johns Hopkins is smoke-free. Complimentary parking is available in the Washington Street Garage. Fees REGISTRATION CUT-OFF DATE: January 18, 2010 Methods of Payment: Payment by check or credit card must accompany the registration form prior to the activity. On-site payments by credit card only. Foreign payments must be by credit card or with a U.S. Dollar World Money Order. The registration fee includes instructional materials, continental breakfast, refreshment breaks and lunch. Early-bird fees Before December 4 After December 4 Physicians/Allied Health Professionals $325 $375 Residents*/Fellows* $200 $250 *with verification of status You will receive a confirmation by e-mail if you have provided your e-mail address. Otherwise confirmation will be sent by mail. If you have not received it by January 18, 2010, call (410) 502-9634 to confirm that you are registered. Certificates of attendance will be mailed by March 1, 2010. The Johns Hopkins University reserves the right to cancel or postpone any activity due to unforeseen circumstances. In this event, the University will refund the registration fee but is not responsible for travel expenses. Additionally, we reserve the right to change the venue to a comparable venue. Under such circumstances registrants will be notified as soon as possible. Late Fee and Refund Policy A $50 late fee applies to registrations received after 5:00 p.m. EST on January 18, 2010. A handling fee of $50 will be deducted for cancellation. Refund requests must be received by fax or mail by January 18, 2010. No refunds will be made thereafter. Transfer of registration to another Johns Hopkins conference in lieu of cancellation is not possible. Hotel and Travel Information We strongly encourage you to book your accommodations at the Hyatt Regency Inner Harbor Hotel, which is the conference headquarters hotel. The Johns Hopkins Office of CME makes every effort to secure the best rate for overnight accommodations. The rate is part of a negotiated conference package that incorporates many services. By staying at the host hotel and booking within the room block, you help us maintain current conference benefits and keep future registration fees reasonable. Please consider this when making your overnight accommodations decision. Hyatt Regency Inner Harbor Hotel Phone: (800) 233-1234 300 Light Street or (410) 528-1234 Baltimore, Maryland 21202 FAX: (410) 665-3362 HOTEL RESERVATION CUT-OFF DATE: DECEMBER 22, 2009 A block of rooms has been reserved for our participants. Call the hotel directly to make your reservation. Specify that you are attending the Johns Hopkins Macula 2010 activity to receive the special room rate of $139, single or double, plus tax. Complimentary transportation will be provided to the activity. On-site parking is available at the hotel at an additional charge. Check-in time is 4:00 p.m. Call United Airlines at (800) 521-4041 for discounted rates and refer to Meeting ID Number 549TJ. Emergency Calls On the day of this activity only, January 23, 2010, direct emergency calls to the Hopkins registration desk, (410) 955-3673. Messages will be posted for participants. Americans with Disabilities Act The Johns Hopkins University School of Medicine fully complies with the legal requirements of the ADA and the rules and regulations thereof. Please notify us if you have any special needs. Acknowledgement Applications for commercial support from health care related industries are pending. A complete list of contributors will be provided in the syllabus. To Register or for Further Information Register Online www.HopkinsCME.edu Register by Phone (credit card only) (410) 502-9634 Register by Fax (866) 510-7088 Confirmation/Certificates (410) 502-9634 General Information (410) 955-2959 E-mail the Office of CME cmenet@jhmi.edu Sponsoring Department [Division] Website: www.http://www.hopkinsmedicine.org/wilmer/services/retina.html For general information, the direct link for this CME activity web page is: http://www.hopkinscme.edu/CourseDetail.aspx/80022730. PROGRAM Saturday, January 23, 2010 7:00 - 7:30 am Breakfast and Registration Note: All presentations will be 10 minutes and then include 5 additional minutes of discussion to follow the presentations. 7:30 - 7:35 Welcome from Activity Directors RETINAL VASCULAR DISEASE Moderators: Morton Goldberg, MD and Hendrik Scholl, MD 7:35 - 7:50 Steroids for Macular Edema in Vein Occlusion? Jennifer Sung, MD 7:50 - 8:05 Ranibizumab for Macular Edema from Vein Occlusion? Peter Campochiaro, MD 8:05 - 8:20 How Does One Choose Steroids or Ranibizumab for Macular Edema in CVO? What Happened to Grid Laser for Macular Edema in BVO? Neil Bressler, MD 8:20 - 8:35 Rationale for Ranibizumab in DME? Susan Bressler, MD 8:35 - 8:50 Focal/Grid Laser for DME ?Is it Relevant in 2010? Alexander Brucker, MD 8:50 - 9:05 How Should We Classify Diabetic Retinopathy? C.P. Wilkinson, MD IMAGING Moderators: Gabriel Coscas, MD and John Huang, MD 9:05 - 9:20 What Does a SD OCT Have That a TD OCT Doesn?t Have? SriniVas Sadda, MD 9:20 - 9:30 With OCT Here to Stay, When Does a Retina Person Still Need Ultrasonography? Cathy Dibernardo, RN, RDMS, ROUB 9:30 - 9:40 How Might One Use OCT When Managing Diabetic Macular Edema? Richard Rosen, MD 9:40 - 9:50 Is There a Role for Wide-Angle Fluorescein Angiographic Imaging? K. Bailey Freund, MD 9:50 - 10:05 Should CMS Be Concerned About Imaging Costs in the Management of Retinal Diseases? John Thompson, MD 10:05 - 10:20 Do We Need OCT to Manage Uveitis? Douglas Jabs, MD, MBA 10:20 - 10:45 Refreshment Break ? Visit Exhibits 10:45 - 10:50 Introduction of Keynote Lecture Daniel Finkelstein, MD 10:50 - 11:10 Keynote Lecture The Evolution of Imaging in Retina: From Fluorescein Angiography in the 1960s to Spectral Domain OCT in the 21st Century Gisele Soubrane, MD, PhD TUMORS Moderators: Jerry Shields, MD and Barbara Hawkins, PhD 11:10 - 11:25 How to Diagnose Uveal Melanoma Carol Shields, MD 11:25 - 11:40 When Should Plaque Radiotherapy be the First Line Treatment for Choroidal Melanoma? James Handa, MD 11:40 - 11:55 Are There Really Masquerades for Uveal Melanoma? Jerry Shields, MD 11:55 - 12:10 What?s New in the Management of Retinoblastoma? David Abramson, MD, FACS 12:10 - 1:00 Lunch NEOVASCULAR AMD Moderators: Frederick Ferris III, MD and Ingrid Zimmer-Galler, MD 1:00 - 1:15 Detecting New Onset CNV: The AMD DOC Study Diana Do, MD 1:15 - 1:30 What?s New with Polypoidal CNV? Lawrence Yannuzzi, MD 1:30 - 1:45 Will There Be a Role for VEGF Trap or Potential Therapies for Neovascular AMD Other than Bevacizumab or Ranibizumab? Quan Dong Nguyen, MD, MSc 1:45 - 2:00 What?s the Status of CATT? Stuart Fine, MD 2:00 - 2:15 What Have We Learned Regarding Retreatments with Ranibizumab from PIER, HORIZON, SUSTAIN, RADICAL, EXCITE, and Others? Carl Regillo, MD, FACS 2:15 - 2:30 How Often Should Patients Return for Follow-up Following Anti-VEGF Treatment for Neovascular AMD? Jeffrey Heier, MD 2:30 - 2:55 AMD Cases and Panel Discussion Susan Bressler, MD (Moderator); Diana Do, MD; Lucian Del Priore, MD, PhD; Carl Regillo, MD, FACS; John Thompson, MD 2:55 - 3:20 Refreshment Break ? Visit Exhibits GEOGRAPHIC ATROPHY IN AMD Moderators: Howard Ying, MD, PhD and James Klancnik Jr, MD 3:20 - 3:35 What is New in Understanding the Genetics of Geographic Atrophy in AMD? Ivana Kim, MD 3:35 - 3:50 What is the Status of Treatments for Geographic Atrophy? Adrienne Scott, MD 3:50 - 4:05 Is There a Role for Autofluorescence in the Management of Geographic Atrophy? Emily Chew, MD SURGICAL RETINA Moderators: Harry Flynn Jr, MD, and James Handa, MD 4:05 - 4:20 What are the Risks and Benefits of Microincisional Vitrectomy? Allen Ho, MD 4:20 - 4:35 When is Scleral Buckling First-Line Therapy for Retinal Detachment? Peter Gehlbach, MD, PhD 4:35 - 4:50 When is Vitrectomy First-Line Therapy for Retinal Detachment? Harry Flynn Jr, MD 4:50 - 5:05 What Advances Have Occurred within the Last 5 Years Regarding Management of ROP? David Bara¤ano, MD, PhD 5:05 - 5:20 Management of Endophthalmitis: What Have We Learned 15 Years After the Endophthalmitis Vitrectomy Study (EVS) Donald D?Amico, MD 5:20 Closing Remarks Neil Bressler, MD Adjourn ? Please complete and return the Evaluation and Credit Report Forms. The Johns Hopkins University School of Medicine takes responsibility for the content, quality and scientific integrity of this CME activity. This schedule is subject to change. SPEAKERS ACTIVITY DIRECTORS Neil Bressler, MD James P. Gills Professor of Ophthalmology Chief, Retina Division Diana Do, MD Assistant Professor of Ophthalmology Quan Dong Nguyen, MD, MSc Associate Professor of Ophthalmology GUEST SPEAKERS David Abramson, MD, FACS Chief, Ophthalmic Oncology Service Memorial Sloan-Kettering Cancer Center New York, New York David Bara¤ano, MD, PhD Vitreoretinal Fellow Emory Eye Center Atlanta, Georgia Alexander Brucker, MD Professor of Ophthalmology Scheie Eye Institute University of Pennsylvania Philadelphia, Pennsylvania Emily Chew, MD Deputy Director Division of Epidemiology and Clinical Research National Eye Institute Bethesda, Maryland Gabriel Coscas, MD Honorary Professor of Clinical Ophthalmology and Chairman Emeritus Clinique Ophtalmologique Universitaire de Creteil Universite de Paris-XII Creteil, France Donald D?Amico, MD Professor and Chairman Department of Ophthalmology Weill Cornell Medical College New York, New York Lucian Del Priore, MD, PhD Robert L. Burch Scholar and Professor Department of Ophthalmology Columbia University New York, New York Frederick Ferris III, MD Director, Division of Epidemiology and Clinical Research National Institutes of Health Bethesda, Maryland Stuart Fine, MD Irene Heinz Given and John LaPorte Given Research Professor of Ophthalmology Chairman and Director Department of Ophthalmology Scheie Eye Institute University of Pennsylvania Philadelphia, Pennsylvania Harry Flynn Jr, MD Professor of Ophthalmology J. Donald M. Gass Distinguished Chair in Ophthalmology Bascom Palmer Eye Institute University of Miami Miller School of Medicine Miami, Florida K. Bailey Freund, MD Clinical Associate Professor New York University School of Medicine Vitreous Retina Macula Consultants of New York New York, New York Jeffrey Heier, MD Vitreoretinal Specialist Ophthalmic Consultants of Boston Boston, Massachusetts Allen Ho, MD Professor of Ophthalmology Wills Eye Institute Thomas Jefferson University Philadelphia, Pennsylvania John Huang, MD Assistant Professor of Ophthalmology Department of Ophthalmology and Visual Sciences Yale University New Haven, Connecticut Douglas Jabs, MD, MBA Professor and Chair Department of Ophthalmology Mt. Sinai School of Medicine New York, New York Ivana Kim, MD Assistant Professor of Ophthalmology Harvard Medical School Massachusetts Eye & Ear Infirmary Boston, Massachusetts James Klancnik Jr, MD Assistant Professor of Clinical Ophthalmology New York University School of Medicine New York, New York Carl Regillo, MD, FACS Professor of Ophthalmology Director, Clinical Retina Research Wills Eye Institute Thomas Jefferson University Philadelphia, Pennsylvania Richard Rosen, MD Vice Chairman and Surgeon Director Director of Ophthalmic Research Retina Consultations and Surgery New York Eye & Ear Infirmary New York, New York SriniVas Sadda, MD Associate Professor of Ophthalmology Director, Medical Retina Unit and Ophthalmic Imaging Unit Doheny Eye Institute University of Southern California Keck School of Medicine Los Angeles, California Carol Shields, MD Professor of Ophthalmology Co-Director, Ocular Oncology Service Thomas Jefferson University Wills Eye Institute Philadelphia, Pennsylvania Jerry Shields, MD Director, Ocular Oncology Service Professor of Ophthalmology Wills Eye Institute Thomas Jefferson University Philadelphia, Pennsylvania Gisele Soubrane, MD, PhD Professor of Clinical Ophthalmology Clinique Ophtalmologique Universitaire de Creteil Creteil, France Lawrence Yannuzzi, MD Professor of Clinical Ophthalmology College of Physicians and Surgeons Columbia University New York, New York JOHNS HOPKINS SPEAKERS Susan Bressler, MD Julia G. Levy, PhD Professor of Ophthalmology Peter Campochiaro, MD George S. and Dolores Dor‚ Eccles Professor of Ophthalmology and Neuroscience Cathy Dibernardo, RN, RDMS, ROUB Associate Professor of Ophthalmology Daniel Finkelstein, MD Professor of Ophthalmology Peter Gehlbach, MD, PhD Associate Professor of Ophthalmology Morton Goldberg, MD Joseph E. Green Professor of Ophthalmology Former Director, Wilmer Eye Institute James Handa, MD Robert Bond Welch Professor of Ophthalmology Barbara Hawkins, PhD Professor Emeritus of Ophthalmology Professor of Epidemiology The Johns Hopkins Bloomberg School of Public Health Hendrik Scholl, MD Visiting Professor of Ophthalmology Adrienne Scott, MD Assistant Professor of Ophthalmology Jennifer Sung, MD Assistant Professor of Ophthalmology John Thompson, MD Visiting Professor of Ophthalmology C.P. Wilkinson, MD Professor of Ophthalmology Howard Ying, MD, PhD Assistant Professor of Ophthalmology Ingrid Zimmer-Galler, MD Associate Professor of Ophthalmology REGISTRATION FORM Course Number 80022730 Macula 2010 ? January 23, 2010 To Register: Online: www.HopkinsCME.edu By fax: (866) 510-7088 By phone (credit card only): (410) 502-9634?? Or mail this form to The Johns Hopkins University, Office of Continuing Medical Education, P.O. Box 64128, Baltimore, Maryland 21264-4128. Include check payable to HOPKINS/80022730 or include credit card information below. PAYMENT MUST ACCOMPANY FORM TO CONFIRM YOUR REGISTRATION. Please type or print clearly: last name first name middle initial primary degree (for name badge) primary specialty preferred mailing address city state ZIP + 4 code country daytime telephone fax number e-mail / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / You will receive confirmation notice by e-mail if you provide your e-mail address. M Check here if you wish to receive e-mail and/or fax notices about upcoming CME activities. What do you hope to learn by attending this activity? Please notify us if you have any special needs. Registration Fees: Early-bird fees Before December 4 After December 4 M Physicians/Allied Health Professionals $325 $375 M Residents*/Fellows* $200 $250 *with verification of status For registrations received after 5:00 p.m. EST on January 18, 2010 include a $50 late fee. On-site registrations are payable only by credit card. Total amount enclosed $ Payment Type: JHU Faculty/Staff Only: Complete registration form and return with appropriate form below to OCME, Turner 20. M Internal Order Number: The ION Data Request Form, can be found online at http://www.hopkinscme.edu/pdfs/IonRequest.pdf. M Tuition Remission: To apply for TR, go to http://benefits.jhu.edu/EduBenefits/tuitionRemission.cfm. This is a non-credit professional development activity. M Check (See instructions on top of form.) 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