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80021870: 22nd Update Frontiers in Research and Clinical Management of Asthma and Allergy: From Bench to Bedside

June 11, 2010
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22nd Annual Update: Frontiers in Research and Clinical Management of Asthma and Allergy Brochure Cover Image


ACCREDITATION STATEMENT
The Johns Hopkins University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
CREDIT DESIGNATION STATEMENT
The Johns Hopkins University School of Medicine designates this educational activity for a maximum of 9.25 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
NURSING CREDITS
ANCC: American Nurses Credentialing Center (ANCC) accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.
AANP: American Academy of Nurse Practitioners (AANP) accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.
OTHER CREDIT
American Academy of Physician Assistants (AAPA)
American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.

Description:
Allergic respiratory diseases have experienced an increased incidence and prevalence over the past decade. Allergic rhinitis now affects 60 million people in the U.S. and asthma, principally defined to be allergic in the majority of patients, is a burden to 24 million people. Allergic rhinitis and asthma represent a major socioeconomic burden to our society, incurring combined direct costs of $16 billion and an additional $10-12 billion in indirect costs. The recent update of the guidelines from the NHLBI, through the National Asthma Education and Prevention Program for the diagnosis and management of asthma, has been widely disseminated and publicized but still has not been effectively implemented in many health care settings across the country. This year’s program will focus on state-of-the-art advances in molecular biology of allergic disease, constructs, including TLR constructs, sublingual immunotherapy, and discussion of rational pharmacotherapy with an emphasis on newly approved therapeutic agents. The conference will take a penetrating look at research on clinical applications for the management of asthma and allergic disease. There will also be roundtable luncheon for faculty and participants to discuss individual cases and clinical problems.

Objectives:
After attending this activity, the participant will demonstrate the ability to:
- Recognize state-of-the-art advances in the molecular biology of allergic disease
- Discuss rational therapeutic decisions in the management of allergy, rhinitis, respiratory disease and asthma
- Apply new therapeutic approaches/diagnosis for allergic disease

Talks

June 11, 2010  8:15 AM to 8:30 AM

Conference Goals and Welcome

Creticos, Peter
June 11, 2010  8:30 AM to 9:15 AM

Airway Inflammation Overview

Borish, Larry
To discuss the presence of eosinophilic and non-eosinophilic asthma and the particular importance of eosinophils to aspirin-exacerbated respiratory disease; To explain the unique role of eosinophils in AERD, in particular as sources of CysLTs, the novel role of LTE4 acting through newly appreciated LTE4-specific receptors, and the capacity of aspirin to directly activate eosinophils in a cyclooxygenase-independent fashion
June 11, 2010  8:30 AM to 1:30 PM

Mini-Symposium I: Airway Inflammation and Its Regulation

Bochner, Bruce
Symposium Chair
June 11, 2010  9:15 AM to 9:45 AM

Biotherapeutic Targets in Asthma: Why They Have Failed

Borish, Larry
To describe novel targets for potential asthma therapeutics - and why they won’t work either
June 11, 2010  9:45 AM to 10:30 AM

Targeted Suppression of Allergic Responses

Valenta, Rudolf
To discuss the possibilities for a targeted suppression of allergic responses
June 11, 2010  11:00 AM to 11:45 AM

Role of Dendritic Cells in the Innate and Adaptive Immune Response

Schroeder, John
To discern how innate vs. adaptive (IgE-dependent) immune responses mediated by dendritic cells could play a role in suppressing or contributing to the allergic phenotype
June 11, 2010  11:45 AM to 12:30 PM

Effect of Immune Modulators on Surface Activation Markers in Allergic Inflammation (sIgE/FCeR1/cytokines)

Saini, Sarbjit
To review surface activation molecules that may be altered by the use of novel immunomodulators
June 11, 2010  12:30 PM to 2:00 PM

Luncheon and Roundtable Discussions: Historical Perspectives on Immunotherapy

Norman, Philip
June 11, 2010  12:30 PM to 2:00 PM

Luncheon and Roundtable Discussions: New Approaches to Immunotherapy

Valenta, Rudolf
To discuss the rationale for the new approaches and to describe how the new immunotherapy approaches work
June 11, 2010  12:30 PM to 2:00 PM

Luncheon and Roundtable Discussions: Novel Immunotherapy Constructs

Creticos, Peter
To discuss clinical cases as pertains to new treatment modalities
June 11, 2010  12:30 PM to 2:00 PM

Luncheon and Roundtable Discussions: Uses of Anti-IgE

Saini, Sarbjit
To review interesting cases from the clinic involving anti-IgE therapy
June 11, 2010  12:30 PM to 2:00 PM

Luncheon and Roundtable Discussions: Uses of Anti-IgE

Paterniti, Miya
June 11, 2010  2:00 PM to 4:00 PM

Mini-Symposium II: Progress in the Development of Therapeutic Agents for Allergic Disease

Creticos, Peter
Symposium Chair
June 11, 2010  2:00 PM to 2:30 PM

TLR Constructs

Creticos, Peter
To discuss when and how to use TLR and CpG vaccines
June 11, 2010  2:30 PM to 3:15 PM

Recombinant Allergen Approaches

Valenta, Rudolf
To define what a recombinant allergen is and how it can be used for diagnosis and therapy
June 11, 2010  3:15 PM to 3:45 PM

Biologics

Bochner, Bruce
To provide an overview of types of biologic therapies and those already approved or undergoing trials for asthma, allergy and related disorders
June 11, 2010  4:00 PM to 6:30 PM

Mini-Symposium III: Progress in the Development of Therapeutic Agents for Allergic Disease

Norman, Philip
Symposium Chair
June 11, 2010  4:00 PM to 4:30 PM

Sublingual Immunotherapy

Creticos, Peter
To discuss when and how to use sublingual immunotherapy
June 11, 2010  4:30 PM to 5:00 PM

Case: When to Consider Allergen Immunotherapy in the Management of the Patient with Allergic Rhinitis and Asthma

Paterniti, Miya
To critically assess when to consider allergen immunotherapy
June 11, 2010  4:30 PM to 5:00 PM

Case: When to Consider Allergen Immunotherapy in the Management of the Patient with Allergic Rhinitis and Asthma

Creticos, Peter
June 11, 2010  5:00 PM to 5:30 PM

Anti-IgE Therapy: Beyond Allergic Asthma

Saini, Sarbjit
To discuss novel roles of IgE in the expression of allergic and non-allergic disease
June 11, 2010  5:30 PM to 6:15 PM

Where Do We Go From Here?

Norman, Philip
To discuss new developments in immunotherapy of allergic rhinitis and asthma
June 11, 2010  5:30 PM to 6:15 PM

Where Do We Go From Here?

Norman, Philip
To discuss new developments in immunotherapy of allergic rhinitis and asthma
June 11, 2010  6:15 PM to 6:30 PM

Closing Remarks

Creticos, Peter

Policy On Speaker And Provider Disclosure

It is the policy of the Johns Hopkins University School of Medicine that the speaker and provider disclose real or apparent conflicts of interest relating to the topics of this educational activity, and also disclose discussions of unlabeled/unapproved uses of drugs or devices during their presentation(s). Johns Hopkins University School of Medicine OCME has established policies in place that will identify and resolve all conflicts of interest prior to this educational activity. Detailed disclosure will be made in the activity handout materials.

Event Information
Johns Hopkins Asthma and Allergy Center
Bayview Medical Campus, 5501 Hopkins Bayview Cir.
Baltimore, MD
Directions

Registration Fee(s)

Physicians – $ 250.00
Residents, Fellows, AHP – $ 150.00

Target Audience(s)

Allergists, pulmonologists, otolaryngologists, internists, pediatricians, family practitioners, nurses, allied health professionals, clinical research personnel and representatives of the pharmaceutical community.

Course Director

Peter Creticos

Course Co-Director

Sarbjit Saini

Contact Info

410.502.9634 or cmenet@jhmi.edu

Departmental Website

Division of Allergy and Clinical Immunology website

Contact Info

General Info: 410.502.9634

Mailing Address:
Johns Hopkins University School
of Medicine
Thomas B. Turner Building
720 Rutland Avenue, Room 20
Baltimore, Maryland 21205-2195

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